Aloha! You're speaking with Dr. Michael SalkinIt sounds as if mites are still present although the only manner in which to confirm their presence is to examine a bit of the ear discharge microscopically. Surolan is quite a high-powered ear ointment but there are much simpler and more reliable therapies for ear mites in cats. For example:Milbemite - a milbemycin solution instilled into each ear once - it's safe and effective.Acarexx - an ivermectin topical solution instilled into each ear once - it's safe and effectiveRevolution - a selamectin spot-on applied topically once or twice 1 month apartIvermectin injectable every 10-14 days for 3 treatmentsFrontline - a 10% fipronil solution 2 drops into each ear once or twice, 2-4 weeks apartIt's important to note that when any otic treatment is used, it should be combined with whole body treatments with an acaricide (mite killer) such as fipronil in order to eliminate any ectopic mites - mites outside the ear. Fipronil spray or spot-on can be used 2-3 times 2 weeks apart.Please respond with further questions or concerns if you wish.
We are seeing flea resistance to Frontline but I haven't seen reports of ear mites becoming resistant. While the two products are compatible, I prefer to use as few drugs in cats as possible. I'd skip the Advocate for a month and, instead, use the Frontline in her ears and on her body for that month.