How JustAnswer Works:

  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.

Ask Dr. Deb Your Own Question

Dr. Deb
Dr. Deb, Dog Veterinarian
Category: Dog
Satisfied Customers: 9140
Experience:  I have been a practicing veterinarian for over 30 years.
60411192
Type Your Dog Question Here...
Dr. Deb is online now

My mums german pointer has recently been diagnosed with cancer

Customer Question

My mums german pointer has recently been diagnosed with cancer effecting her liver and been given a poor prognosis. She has not seemed to be suffering or in pain and the main symptoms have been weight loss, anorexia and lethargy. Over the last 24 hours she has developed persistent vomiting; I was wondering if motilium [domperidone] might be helpful? I know this is one of the least hepatotoxic antiemetics for humans and my mum has some but I have been unable to find anything online to indicate its safety for dogs.
Just looking for some thing to settle and make her feel comfortable......thanks Spencer
Submitted: 2 years ago.
Category: Dog
Expert:  Dr. Deb replied 2 years ago.

Hello, I'm Dr. Deb.

I recently came online and see that your question about Molly hasn't been answered. I'm so sorry that you've had to wait for a response,but if you still need assistance, I'd like to help if I can.

First, let me tell you how sorry I am that Molly has been diagosed with cancer. I know how distressing this must be for your entire family.

To answer your question, domperidone can be given to dogs as an anti-vomiting agent although it's not used in small animals very often. It is primarily metabolized and excreted through urine and feces.

As to Cautions with it's use, the following is taken from Plumbs Veterinary Drug Handbook:

Domperidone should not be used in animals with known hypersensitivity to it or when GI obstructions are present or suspected.

Because domperidone is potentially a neurotoxic substrate of P-glycoprotein, it should be used with caution in those herding breeds (e.g., Collies) that may have the gene mutation (MDR1) that causes a nonfunctional protein.

Drug interactions:

1. Opioids may reduce the efficacy of domperidone

2. It may alter the absorptive characteristics of sustained -release or eneteric coated oral medicaions by decreasing GI transit times

 

The dose would be 2–5 mg (total dose) two to three times a day. While it would be illegal for me to advise you to use a drug which has been dispensed for a human, I can provide the dosage information for a canine patient which I have done.

I hope this helps although, again, my apologies for the delayed response. Deb

Customer: replied 2 years ago.

Thanks for the reply...very clear. I appreciate it. I shall go visit and see how she's doing


Spencer

Expert:  Dr. Deb replied 2 years ago.

Spencer:
You're more than welcome.

I hope you'll find that Molly is feeling more comfortable.

While I doubt if it will be strong enough, your mom could also safely give her over the counter Famotidine although it may be difficult to find in the UK. The dose would be 1/4th mg/lb twice a day. Another option would be Omeprazole at a dose of 0.5 mg/lb once a day.

Of course, your vet will have stronger anti-emetics such as Cerenia . This drug comes in an injectable form which lasts 24 hours, but is also available in a pill form. If effective, it can be given for 5 days in a row, and then skip two days before restarting.
This drug has primarily been used to control vomiting but it was found to have appetite stimulant properties and is sometimes used for this purpose.

Good luck. Deb

What Customers are Saying:

 
 
 
  • It was so professional, so personally concerned (as we were) and you answered all of our questions. George and I are so happy that I found ""JustAnswer"" on my Google search -- you are now in my ""Favorites"" list! And, yes we do love our kitty - she makes our life complete! Bev & George
< Previous | Next >
  • It was so professional, so personally concerned (as we were) and you answered all of our questions. George and I are so happy that I found ""JustAnswer"" on my Google search -- you are now in my ""Favorites"" list! And, yes we do love our kitty - she makes our life complete! Bev & George
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C.
  • This expert is wonderful. They truly know what they are talking about, and they actually care about you. They really helped put my nerves at ease. Thank you so much!!!! Alex
  • Thank you for all your help. It is nice to know that this service is here for people like myself, who need answers fast and are not sure who to consult. GP
  • I couldn't be more satisfied! This is the site I will always come to when I need a second opinion. Justin
  • Just let me say that this encounter has been entirely professional and most helpful. I liked that I could ask additional questions and get answered in a very short turn around. Esther
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C.
 
 
 

Meet The Experts:

 
 
 
  • Rebecca

    Rebecca

    Dog Veterinarian

    Satisfied Customers:

    293
    Veterinarian for more than 30 years
< Last | Next >
  • http://ww2.justanswer.com/uploads/TO/tomasicvet/2011-3-15_20483_RTI.64x64.jpg Rebecca's Avatar

    Rebecca

    Dog Veterinarian

    Satisfied Customers:

    293
    Veterinarian for more than 30 years
  • http://ww2.justanswer.com/uploads/MS/msb13sm/2011-3-7_52612_Dr.B.64x64.JPG Dr. Matt's Avatar

    Dr. Matt

    Veterinarian

    Satisfied Customers:

    2354
    DVM - 13 years experience in canine medicine and surgery.
  • http://ww2.justanswer.com/uploads/DR/Dr. Gene/2012-6-29_2247_20120223174645649.64x64.jpg Dr. Gene's Avatar

    Dr. Gene

    Veterinarian

    Satisfied Customers:

    1048
    DVM degree from Ontario Veterinary College
  • http://ww2.justanswer.com/uploads/VE/Vet help/2012-11-3_20182_Avatar2.64x64.png Vet help's Avatar

    Vet help

    Veterinarian

    Satisfied Customers:

    963
    12 yrs experience as a small animal veterinarian; 21 yrs exp. in the animal care field
  • http://ww2.justanswer.com/uploads/DE/debkatreyn/2011-11-28_33650_682e.64x64.jpg Dr. Debbie's Avatar

    Dr. Debbie

    Dog Veterinarian

    Satisfied Customers:

    902
    Companion animal veterinarian practicing for over 10 years.
  • http://ww2.justanswer.com/uploads/KR/kritrdr/2014-3-26_152042_Dr.Gray1.64x64.jpg Dr. Dan's Avatar

    Dr. Dan

    Dog Veterinarian

    Satisfied Customers:

    2143
    12 years of experience with domestic and exotic dogs, PLEASE rate my service when satisfied.
  • http://ww2.justanswer.com/uploads/DJ/djan2000/djan2000_avatar.64x64.jpg Dr. Dave's Avatar

    Dr. Dave

    Veterinarian

    Satisfied Customers:

    2053
    21 years small animal general and emergency practice
 
 
 

Related Dog Questions