Hello, I'm Dr. Deb and I'll do my best to help you today. While no one can 100% assure that a rabies vaccination will not cause any side effects for your dogs, I can tell you that the largest percentage of dogs experience no reactions whatsoever. There might be a slight increase in the incidence of reactions to a rabies vaccine as opposed to other vaccines which a dog might receive such as DHPP (Distemper, Hepatitis, Parvo, Parainfluenza) because it is what's known as a killed vaccine as opposed to a modified live one. However, that incidence is still not terribly high. The fact that they both have epilepsy, however, would not predispose them in any way to reacting in an adverse way.The most commonly seen vaccine reactions that are seen are a mild fever with resultant loss of appetite and mild lethargy approximately 24 hours after the vaccine is given. These effects tend to last another 24 hours.Occasionally hives or facial swelling (angioedema) can be seen within several hours post-vaccination. Administration of an anti-histamine such as Diphenhydramine (Benadryl) is usually sufficient for this problem to resolve. A few dogs might require steroids before improvement is seen.Even less commonly seen would be an immediate anaphylactic reaction such that diarrhea, vomiting and balance issues might be seen. Fortunately, this is fairly rare. I've read some statistics which indicate 1 out of 15000 dogs will have just such a reaction.There are certain breeds such as Weimaraners or Akitas who might experience immune mediated reactions after a vaccine but I'm not aware that these problems are seen in JRT's. So, while side effects aren't common, they certainly can occur. As to predicting which dogs will be affected, this isn't something that can be determined ahead of time, unfortunately.I hope this helps. Deb
Thanks for the rating and bonus; it's greatly appreciated.I hope you and your JRT's enjoy the trip:) Regards, DebKindly ignore the information request.