My dog has a heart murmur and just recently she chooses to sit alone in a quiet room, as well as shaking and panting. Are these connected to the heart murmur?
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This does sound concerning for Lily. The answer is maybe. If she is truly having difficulty breathing with increased effort to move air (not just regular panting) then this could be related to heart failure. You should look at her gum color, which under normal circumstances should be a nice pink. If she has darkly colored gums then look at her tongue. If the color of her gums/tongue is a blue or gray, then this is a medical emergency and you need to haver her seen right away (then this does perhaps signal a heart problem or a heart arrhythmia), but the change in gum color does not always come with heart issues.
An alternative cause for isolating herself with shaking and panting is that she is painful. Pain most commonly comes from the spine (neck/back) or abdominal/stomach. It is good to do a once-over to feel these areas. If she reacts in any of these areas, then she is painful and this is an indication to have her seen. If her symptoms resolve within the next hour, then monitor her closely. I would advocate have her seen in the next few days by her vet for a good exam, if this all does resolve to normal.
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She doesn't appear to be in pain and her gums are pink