You're quite perceptive. A hypothalamic tumor should always be on the differential diagnosis list for a polydipsic, polyuric, and polyphagic geriatric particularly if you've ruled out the common villains such as diabetes mellitus and Cushing's. I would like to confirm that that's the case, however. Can you upload a copy of his test results to our conversation? I understand that you might not have a copy at home but his vet can give you one which you can scan into your computer and then give me the file link or you can photograph the pages and upload them by using the paperclip icon (if you can see that icon) or by using an external app such as dropbox.com/
Please note that atypical Cushing's remains a possibility if a sex hormone panel (progesterone, 17-hydroxyprogesterone, estradiol, androstenedione, testosterone) hasn't been performed. Excesses in these hormones also can cause cushingoid symptoms.
Perhaps. The sex hormone-related Cushing's will be found secondary to an adrenal tumor (particularly adenocarcinomas) and a nonsteroidal antiinflammatory drug might have a chemotherapeutic effect on such a tumor. Piroxicam is the NSAID we're most aware of having such an effect and meloxicam is in the same class of drugs. You're quite welcome. I can't set a follow-up in this venue so please return to our conversation - even after rating - with the additional information at your convenience. You can bookmark this page for ease of return.
Thank you for your kind accept. I appreciate it.