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Can you please remove the power to the unit (so unplug it from the power socket).
Then wait 10 minutes, connect the power again to the box, turn it on and tell me please if it is now operating correctly.
Let me know the results please
Do you have a smartphone? Point the end if the remote at the smartphones camera with the camera on and see if you see the lights flash when you press a button.
It can see infrared, do you see anything with it?
yes, the buttons on the device are independent of the remote.
If they are not working at all Barry then we know It is the mainboard that has faulted. Everything else has been ruled out.
I am really sorry about this and you are going to have to return the unit to have it replaced. It will be covered by the warranty if this has not expired, and the replacement will be done at no cost to you.
I am really sorry about this, and if you have problems, or would like any additional information or assistance, please do not hesitate to let me know.
And if you can take a second to rate my service by clicking one of the stars at the top of the page, then submit, that would be greatly appreciated.