Hello & Welcome to JustAnswer. My name is Kamil and i will do my best to assist you.
Can you go to Settings > Privacy >Microphone.
Ensure, Microphone is turned on for Skype and other apps.
Then reboot the iPad by holding the power and the sleep wake button and test again to see if it works.
Can you do it again by going to Settings > Privacy >Microphone.
Also, tell me what apps are listed there under Microphone?
Please leave me a message when you are back.
When you make a call to someone, do you see this message:Grant access to your microphone in device settings for ... to hear you.See image below:
That means, now you do not get that message anymore.
How many times approx. did you reset?
Can you open Voice Memos
And try to record something, then see if you can hear back.
I am sorry to be the bearer of bad news but this appears to be a hardware fault with mic.
BUT we can do one more thing to check this.
And that would be to restore iPad using iTunes.
There are already a number of issues reported with Mic dying after the upgrade. However, we can do a reinstall to confirm this.
Do you have a computer with iTunes on it?
And are you talking to me from the computer or from the iPad ?
Okay. I will type instructions here that will need to be performed on the computer and iPad.
Please note down all instructions before proceeding.
Step 1:Connect your USB cable to your computer but not to the iPad.
Step 2:Turn off the iPad: Press and hold the Sleep/Wake (top) button for a few seconds until the red slider appears, then slide the slider. Wait for the device to turn off. While pressing and holding the Home button down (the round button in the center), connect the USB cable to the iPad this will turn the device back on.
Continue holding the Home button until you see the Connect to iTunes screen. When this screen appears, you can release the Home button:
iTunes should automatically open and say that iPad has been detected in recovery mode.
The iTunes will display an option to "Restore iPad", click the "Restore iPad" button. It will take between 30 to 50 minutes for it to Complete. (Do not disconnect the iPad from Computer while it is doing the restore)
Once the restore is complete, it will ask you to set it up as a new iPad or restore from a back up (if any is available).
You can then make your selection to either set it up as new (which will delete all previous data) OR restore from back up if any is available.
The setup prompt (if you set it up as new) may ask you to set a new passcode, just skip that option or set a new passcode that you can easily remember and make a note of it.
Once you restore the iPad from iTunes check if Skype works, if it does then restore from the backup on iCloud. When you do a restore from the back up on iCloud, it will restore images, contacts etc..
Yes, please come to me and let me know the results.