How JustAnswer Works:

  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.

Ask Dr. D. Love Your Own Question

Dr. D. Love
Dr. D. Love, Doctor
Category: Medical
Satisfied Customers: 17557
Experience:  Family Physician for 10 years; Hospital Medical Director for 10 years.
21597572
Type Your Medical Question Here...
Dr. D. Love is online now

I am having a clean habit ,during the Elisa test for the premarital

Customer Question

I am having a clean habit ,during the Elisa test for the premarital course it read a value 0.30 they told its non reactive ,my question is why it reads like that they told the border line is 0.1 to .9 and above 1 is problem? but how it could read 0.3
Submitted: 3 years ago.
Category: Medical
Expert:  Dr. D. Love replied 3 years ago.
Thank you for using JustAnswer. I will be glad to assist you today.

I assume that you mean a test for herpes simplex virus (HSV), although a similar issue is present with many of the ELISA tests.

When performing an ELISA test for HSV, there can be a small amount of cross-reactivity with other antibodies that are present in the body. Therefore, the result is an index (or ratio) between what is measured and what could be measured from cross-reactivity. When there is an index report of 0.3, that does not mean that there is a small amount of antibodies against the HSV, it means that there is a small amount of other antibodies that cross-react with the ELISA test.

In reality, a value that is 0.9 - 1.1 s considered borderline and requires a recheck after a period of time to see if the value is increasing. There also is some evidence that someone with a mildly positive result also may be a false positive from cross-reactivity, and the only way to determine this is to perform a more specific test, a western blot test.

The primary limitation with this test is the recognition that it takes some time (months) for antibodies to form, so if someone were recently exposed or concerned that they might have been recently exposed, a test that has been done early would not be meaningful. However, in your case, it does not sound like you had a recent worrisome exposure, so this should not be an issue.

Therefore, in your situation, a value of 0.3 is clearly negative and is due to cross-reactivity, and there is no reason for you to be concerned about the possibility of infection based on this lab result.

My goal is to provide you with excellent service and a complete answer. If I have completely answered your question, please remember to provide a positive rating so that I can be compensated for my time. If you have any further questions or need clarification, please let me know.



What Customers are Saying:

 
 
 
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me FROM a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O.
< Previous | Next >
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me FROM a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O.
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C.
  • This expert is wonderful. They truly know what they are talking about, and they actually care about you. They really helped put my nerves at ease. Thank you so much!!!! Alex
  • Thank you for all your help. It is nice to know that this service is here for people like myself, who need answers fast and are not sure who to consult. GP
  • I couldn't be more satisfied! This is the site I will always come to when I need a second opinion. Justin
  • Just let me say that this encounter has been entirely professional and most helpful. I liked that I could ask additional questions and get answered in a very short turn around. Esther
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C.
 
 
 

Meet The Experts:

 
 
 
  • Family Physician

    Family Physician

    Doctor

    Satisfied Customers:

    2418
    GP with over 27 years experience including emergency medicine
< Last | Next >
  • http://ww2.justanswer.com/uploads/FA/FamilyPhysician/2013-8-31_191624_JA550x500Photo.64x64.jpg Family Physician's Avatar

    Family Physician

    Doctor

    Satisfied Customers:

    2418
    GP with over 27 years experience including emergency medicine
  • http://ww2.justanswer.com/uploads/DO/DoctorRich/2012-9-12_72454_Doctorweb.64x64.jpg Dr. Natasha's Avatar

    Dr. Natasha

    Doctor

    Satisfied Customers:

    7887
    American Board Certified in Emergency Medicine, Ivy League trained
  • http://ww2.justanswer.com/uploads/DR/DrK99/newpic2.64x64.jpg Dr. K.'s Avatar

    Dr. K.

    Board Certified MD

    Satisfied Customers:

    255
    Board certified with experience in primary care.
  • http://ww2.justanswer.com/uploads/agketch/2008-7-14_184046_drketchresized.jpg Dr. Ketch's Avatar

    Dr. Ketch

    Board Certified Physician

    Satisfied Customers:

    76
    Medical Degree, Former Assistant Professor at School of Medicine at Yale University
  • http://ww2.justanswer.com/uploads/JA/JACUSTOMERjtu60wne/2011-2-14_183449_passportphoto2.64x64.jpg docwithheart's Avatar

    docwithheart

    Board Certified Physician

    Satisfied Customers:

    0
    Board certified pediatrician, with special experience in general pediatrics, hospital pediatrics, and pediatric cardiology
  • http://ww2.justanswer.com/uploads/DR/drappapo/2013-8-16_22576_drdavid.64x64.jpg Dr. David's Avatar

    Dr. David

    Board Certified Physician

    Satisfied Customers:

    224
    Treat children/young adults, former chief resident, multiple publications
  • http://ww2.justanswer.com/uploads/TA/tazechip/2012-6-7_135230_drpic.64x64.png Dr. Chip's Avatar

    Dr. Chip

    Board Certified Physician

    Satisfied Customers:

    12373
    20 yrs. in practice, includinge surgery, general medicine, addiction medicine and pain.