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I am Mysticdoc, experienced Internal Medicine Specialist.
I am here to help you with your concerns.
The swelling of the legs is not related to the levothyroxine.
However, if your hypothyroidism has worsened, that can cause swelling of the legs.
That is unlikely, since you do not have significant fatigue.
The next possibility is the venous swelling.
DVT is a strong possibility given the long distance travelling.
Impaired venous circulation can cause leg swelling on standing or walking.
Another possibility can be due to the altitude difference.
This can also precipitate venous swelling due to the lack of acclimatization.
DVT can cause serious complications if not addressed early.
Hence, you should go to the local hospital to get a doppler ultrasound of the leg veins to rule out DVT.
Compression stockings will be helpful to prevent swelling during walking.
Low salt diet, fluid restriction also will help with the swelling.
Other possibilities of leg swelling can be underlying kidney problem, heart disease which can be ruled out in the hospital also.
Low dose diuretic ( hydrochlorothiazide) can be used if no other problem is found to minimize the swelling.
Natural food items with diuretic action are celery, dandelion root, caffeine.
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