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Dr.Saleem
Dr.Saleem, Doctor
Category: Medical
Satisfied Customers: 1724
Experience:  MBBS
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Hello I was wondering if there any interactions when taking

Customer Question

Hello I was wondering if there any interactions when taking l tyrosine, while you are taking prozac for depression
Submitted: 4 years ago.
Category: Medical
Expert:  Dr.Saleem replied 4 years ago.
Hi
Welcome to JA!
Thanks for the question..

There is no known interaction between prozac and L-tyrosine and can be taken together safely.

If you have more questions, feel free to ask!
Expert:  Dr.Saleem replied 4 years ago.
Hi Ajay!

The Prozac (fluoxetine) is a serotonin re-uptake inhibitor (SSRI) and increases the levels of serotonin in the brain which in turn stimulates peacefulness and sleep.

Tyrosine, which can also be synthesized in the body from phenylalanine, is found in many high-protein food products such as chicken, turkey, fish, peanuts, almonds, avocados, milk, cheese, yogurt, cottage cheese, lima beans, pumpkin seeds, sesame seeds, bananas, and soy products.

In dopaminergic cells in the brain, tyrosine is converted to levodopa by the enzyme tyrosine hydroxylase (TH). Dopamine can then be converted into the catecholamines norepinephrine (noradrenaline) and epinephrine (adrenaline). The thyroid hormones triiodothyronine (T3) and thyroxine (T4) in the colloid of the thyroid also are derived from tyrosine.

So Tyrosine is not taken with MAO drugs (also antidepressants: which increase the levels of dopamine/NE by inhibiting the enzyme which breakdowns these neurotransmitters) as it increases the levels to neurotransmitters to the toxic levels..

The MAO inhibitors are contraindicated to be taken with SSRIs as this can precipitate another set of symptoms called serotonin syndrome.

But there is no such interaction known between L-tyrosine and SSRIs (which selectively increase the levels of serotonin)

L-tryptophan is another supplement which interacts with the prozac and can produce serotonin syndrome.


In hope the answer is helpful..
If you have more questions, plz ask..