How JustAnswer Works:

  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.

Ask Dr. Robert Your Own Question

Dr. Robert
Dr. Robert, Doctor
Category: Medical
Satisfied Customers: 6680
Experience:  M.B.B.S, Experienced Family Physician
8493425
Type Your Medical Question Here...
Dr. Robert is online now

I have recently had a routine psa test which resulted in 7.9.

Customer Question

I have recently had a routine psa test which resulted in 7.9. My last test ten years ago was 2.9. I am 61 years old and have no urinary symptoms but have difficulty ejaculating which I have been told is probably due to my medications for sero negative arthritis. I inject myself every week with Metharexate. Now I have discovered Methatrexate could influence my psa result. I have been asked to have a biopsy next week and now don't know whether to go ahead with it. What do you advise?
Submitted: 3 years ago.
Category: Medical
Expert:  Dr. Robert replied 3 years ago.
Hello
Welcome to justanswer.com and thank you for your question.
I'm so sorry to hear of your discomfort.I will do whatever I can to help answer your questions:

Methotrexate is a chemical compound often used to suppress the immune system in order to treat certain diseases. It can also lead to altered PSA levels.

PSA stands for prostate specific antigen. It is often used as a screening test to detect prostatic cancer.

Methotrexate can interfere with the PSA test.

Those with a PSA between four and 10 have a 25% chance of having prostate cancer and if the PSA is higher than 10, the risk increases to 67%.

Higher PSA does not always indicate for prostate cancer.If a higher than normal level is found, it may be an indication of prostate infection, inflammation, enlargement or cancer.

Although you do not have any urinary symptoms,but considering your age factor & high PSA levels(most probably due to methotrexate),you should have the following tests:

-Digital rectal examination (DRE),
-PSA velocity.
-Rectal ultrasound
-Prostate biopsy,
-Urine flow
-Percent-free PSA.

As you have already underwent -Digital rectal examination (DRE) & MRI scan with normal reports,further a prostate biopsy if done will make you sure 100% safe & will rule out the cancer.So I advice you to go for the prostate biospy.A prostate biopsy is the best test to detect/rule out prostate cancer.

Hope this helped.

My goal is to provide you with excellent service – if you feel you have gotten anything less, please reply back, I am happy to address follow-up questions.

Thank you

Kind Regards,
Dr. Robert



What Customers are Saying:

 
 
 
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me FROM a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O.
< Previous | Next >
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me FROM a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O.
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C.
  • This expert is wonderful. They truly know what they are talking about, and they actually care about you. They really helped put my nerves at ease. Thank you so much!!!! Alex
  • Thank you for all your help. It is nice to know that this service is here for people like myself, who need answers fast and are not sure who to consult. GP
  • I couldn't be more satisfied! This is the site I will always come to when I need a second opinion. Justin
  • Just let me say that this encounter has been entirely professional and most helpful. I liked that I could ask additional questions and get answered in a very short turn around. Esther
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C.
 
 
 

Meet The Experts:

 
 
 
  • Family Physician

    Family Physician

    Doctor

    Satisfied Customers:

    2418
    GP with over 27 years experience including emergency medicine
< Last | Next >
  • http://ww2.justanswer.com/uploads/FA/FamilyPhysician/2013-8-31_191624_JA550x500Photo.64x64.jpg Family Physician's Avatar

    Family Physician

    Doctor

    Satisfied Customers:

    2418
    GP with over 27 years experience including emergency medicine
  • http://ww2.justanswer.com/uploads/DO/DoctorRich/2012-9-12_72454_Doctorweb.64x64.jpg Dr. Natasha's Avatar

    Dr. Natasha

    Doctor

    Satisfied Customers:

    7887
    American Board Certified in Emergency Medicine, Ivy League trained
  • http://ww2.justanswer.com/uploads/DR/DrK99/newpic2.64x64.jpg Dr. K.'s Avatar

    Dr. K.

    Board Certified MD

    Satisfied Customers:

    255
    Board certified with experience in primary care.
  • http://ww2.justanswer.com/uploads/agketch/2008-7-14_184046_drketchresized.jpg Dr. Ketch's Avatar

    Dr. Ketch

    Board Certified Physician

    Satisfied Customers:

    76
    Medical Degree, Former Assistant Professor at School of Medicine at Yale University
  • http://ww2.justanswer.com/uploads/JA/JACUSTOMERjtu60wne/2011-2-14_183449_passportphoto2.64x64.jpg docwithheart's Avatar

    docwithheart

    Board Certified Physician

    Satisfied Customers:

    0
    Board certified pediatrician, with special experience in general pediatrics, hospital pediatrics, and pediatric cardiology
  • http://ww2.justanswer.com/uploads/DR/drappapo/2013-8-16_22576_drdavid.64x64.jpg Dr. David's Avatar

    Dr. David

    Board Certified Physician

    Satisfied Customers:

    224
    Treat children/young adults, former chief resident, multiple publications
  • http://ww2.justanswer.com/uploads/TA/tazechip/2012-6-7_135230_drpic.64x64.png Dr. Chip's Avatar

    Dr. Chip

    Board Certified Physician

    Satisfied Customers:

    12373
    20 yrs. in practice, includinge surgery, general medicine, addiction medicine and pain.