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Dr. David
Dr. David, Board Certified MD
Category: Medical
Satisfied Customers: 46959
Experience:  Board Certified Physician
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can clonidine cause behavioural disinhibition?

Customer Question

can clonidine cause behavioural disinhibition?
Submitted: 3 years ago.
Category: Medical
Expert:  Dr. David replied 3 years ago.

Dr. David :

This is Dr. David

Dr. David :

clonidine is centrally acting antihypertensive agent used to bring down blood pressure.

Dr. David :

it stimulates alpha 2 adrenergic receptors

Dr. David :

it can cause agitation and nervousness, headaches and withdraw symptoms if you stop it quickly.

Dr. David :

so the agitation could be causing the inappropriate outburts

Dr. David :

no other blood pressure medications are controlling your blood pressure?

Dr. David :

I have to see a patient for a moment

Dr. David :

I'll be back with you in 10 minutes.

Dr. David :

thanks.

Customer:

The behaviour occurred whilst I was using a clonidine patch (Catapres), attending a meeting as an invited observer. I am aware that 'behavioural disturbance' is a listed unusual side effect. I just wondered whether 'disinhibition' would be included in that. It has got me into a lot of trouble - never experienced this before or since. I DEFINITELY was not in control of my actions. In fact one could say I was an observer of myself!

Dr. David :

back now.

Dr. David :

do you have questions?

Customer:

This 'disinhibition' occurred whilst I was using the patch, not afterwards. I can find little information as to whether 'disinhibition' would be included as a side effect of clonidine. I never had it before using the patch and it stopped right after I removed the patch. Your opinion would be appreciated

Dr. David :

I think the clonidine caused agitation and this is what caused the outburst.

Customer:

Dr David - thank you for your opinion.

Dr. David :

you are welcome

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