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acyclovir can cause rash and muscle aches as side effects
but any sort of viral infection or cold or flu infection can cause swollen glands and aches and pains
you could be coming down with a viral infection.
if your symptoms get worse, or if you develop fevers you should see a doctor or go to the urgent care center.
you should show this mole to your doctors as well to make sure it is benign.
or you can upload a photo of it here if you want me to look at it.
usually acyclovir doesn't cause moles.