Hi there, This is Dr Basu, Experienced Specialist. I am here to address your concerns and provide great service.
You are doing right things for treatment.
Aldehyde dehydrogenase deficiency will cause consistent symptoms every time you drink alcohol.
But if these symptoms never happened before, then this is likely related to the recent use of SSRIs.
Alcohol can react with the SSRIs which sometime may take long to get out of your system.
also are you taking any other medications currently?
Ok that makes it little different issue
if you had problem before with alcohol, then you are likely intolerant to the alcohol from enzyme deficiency
this causes build up of acetaldehyde which causes flushing like reactions.
Fermented alcohols like wine also contain tyramine, histamine, sulfites which only make the reaction worse
So in your case, SSRI is not causing the problem since you do not take them now.
However there are other medications that can intensify alcohol related flushing
yes they are also mediated by the acetaldehyde as it triggers catecholamine release.
that means acetaldehyde increases the catecholamines the stress hormones
catecholamines increase heart rate, blood pressure etc.
SSRIs can actually reduce the catechlamine related symptoms.
Well, studies have shown people with problem with alcohol metabolism are at increased risk of throat cancer due to the toxic effect from acetaldehyde
so it is not that good for you in other words
that is possible,
but your reactions are typical with ADH deficiency
no you cannot --not yet
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