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The combination of these two drugs and alcohol is dangerous
Tramadol and amitriptyline when used together can induce seizures
Use of these drugs along with alcohol can induce irregular heart beat, cause increased and extreme drowsiness , impaired thinking and judgement and respiratory depression among other effects
Both tramadol and amitriptyline decrease seizure threshold and additive effect of both can induce seizures.Alcohol can cause decrease inmetabolism of amitriptyline and consequent increased levels of amitriptyline.This would further exaggerate the harmful interaction between these two drugs and alcohol.
You should show all I have written to her so that she avoids taking all three together.
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