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Ken, Postgraduate doctor
Category: Medical
Satisfied Customers: 6559
Experience:  Working as a Doctor who Cares since 2001.
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Can indeterminate uptake in the medistinial nodes on a pet

Customer Question

Can indeterminate uptake in the medistinial nodes on a pet scan mean metastases ?
Submitted: 2 years ago.
Category: Medical
Expert:  Ken replied 2 years ago.
I am Dr Ken and I will be helping you today.
It is less likely and not specific for metastasis. I would also see for other imaging signs on associated CT scan though. Can you give me the CT report?
Customer: replied 2 years ago.

How do I attach it ?

Expert:  Ken replied 2 years ago.
You may wish to attach it here by clicking on tab of 'clip' above the box.
Upload the report at sites like and give me a link here to see.
Customer: replied 2 years ago.

I cant seem to do this . But report says ... Uptake is indeterminate in the medistinial / hiliar nodes . This could be metastases or poss represent a sarcoid like reaction .

Expert:  Ken replied 2 years ago.
Intermediate uptake does not always mean metastasis for sure. Metastasis would show high uptake on PET study.
I would not panic of cancer spread with this single report.
Next step - Close interval follow-up on size and number of nodes would give us more answers.
Customer: replied 2 years ago.

The thing is surgery was done this year for colon tumor and then a recent scan showed 2 liver lesions .

one with 5.2 uptake and one with 2.8.

they say the 5.2 one Is a met. What could the other one be? Can it be a killed met thru xeloda which he took 4 cycles of?

Expert:  Ken replied 2 years ago.
The other may be metastasis with less function or aggression {can be due to the drug}.
Customer: replied 2 years ago.

Could this mean it's a killed met due to xeloda?

can chemo kill some but still not kill some ?

Expert:  Ken replied 2 years ago.
It means that the activity {growth aggression} is less in that node.
Customer: replied 2 years ago.

Ok can the chemo irinotecan stop further met?

Expert:  Ken replied 2 years ago.
Chemotherapy reduces the spread of the cancer and aggression too. It may not completely stop the spread though.
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