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there, This is Dr Basu, Experienced Specialist. I am here to address your concerns and provide great service.
I do understand your concern.
Your wife may have had seizures from AD itself.
However, Donepezil can worsen the seizure problem potentially.
Studies have shown the better outcomes with memantine and donepezil combination.
And Memantine alone is also stronger than donepezil alone.
So, this is a complex decision making process.
If your wife does not get seizures any further with an antiepileptic medication like Levatiracetam, then donepezil may be continued at 5 mg daily with memantine.
But any further seizure episode should warrant discontinuation of donepezil completely.
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