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My question is for an adrenal endochrinologist.My basal (early follicular phase) prednisolone is elevated (10nmol/l ) and will not fall to zero. Day 21 progesterone normal indicating ovulation. Initially it was thought that it was related to failure of corpus luteal regression but has remained unchanged for 4 cycles. Menstrual cycles regular 28 days but spotting intermenstral spotting occurs occasionally. Is the elevated progesterone adrenal and do you believe in the so called "pregnenolone steal"? Is the high basal progesterone relevant with respect to endometrial development and fertility. Does it require any treatment - eg prednisolone, oestrogen or DHEA supplementation?
Is there an endochrinologist that my question can be forwarded to?
I'm happy to wait
Thanks. The problem is I've posed this question already to 3 fertility doctors. I dont have a residual corpus luteum cyst. I understand follicular phase progesterone is adrenal in origin. Therefore if my elevated progesterone is adrenal - then why is it high? I'm sure I don't have CAH as I have no features of testosterone xs.
My initial question related to "pregnenolone steal". Is this a recognised condition or a load of rubbish? Ie would the high follicular phase progesterone indicated that I'm producing less estrogrogen and hence endometrium will not develope adequately?