How JustAnswer Works:
  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.
Ask Dr. Phil, MD Your Own Question
Dr. Phil, MD
Dr. Phil, MD, Board Certified Physician
Category: Medical
Satisfied Customers: 55454
Experience:  GP in the United States
55099014
Type Your Medical Question Here...
Dr. Phil, MD is online now

After first session of oxyplatin chemotherapy my fathers ALP

Customer Question

After first session of oxyplatin chemotherapy my fathers ALP level
Has jumped from 75 to 225. What could be the reason ?
He has metastic colorectal cancer with liver mets
Submitted: 2 years ago.
Category: Medical
Expert:  Dr. Phil, MD replied 2 years ago.
still need help?
Customer: replied 2 years ago.

Yes please

Expert:  Dr. Phil, MD replied 2 years ago.
Thanks for this question. This could be related to progression/non response of the cancer. It could simply be toxicity from the chemo as well. What is his CEA level trend?
Customer: replied 2 years ago.

Well it was 65 just before start of chemo . The chemo is ixy

Expert:  Dr. Phil, MD replied 2 years ago.
we will need to trend the CEA to see if he is responding.
Customer: replied 2 years ago.

It was 60 beofre chemo and after the first infussion it jumped to 80.

so was a rise within 3 weeks . Surely it should have reduced right ?

also does metastic colon cancer respond tI chemo

or v few ppl do ?

Expert:  Dr. Phil, MD replied 2 years ago.
That is correct. The rise in CEA could be due to inflammation during treatment as well. You need to check it after chemo is done
Customer: replied 2 years ago.

Yes I suppose your right . But is the ALP rise not too much from 75 to 225? Could that b liver failure ?

Expert:  Dr. Phil, MD replied 2 years ago.
No that is not liver failure. The number would be much higher
Customer: replied 2 years ago.

Ok that's a relief then . Are 8 mets in the liver alot ? One is 10 cm

Expert:  Dr. Phil, MD replied 2 years ago.
Yes, that is a lot. I'm sorry
Expert:  Dr. Phil, MD replied 2 years ago.
Yes, that is a lot. I'm sorry
Customer: replied 2 years ago.

Are a lot of ppl generally resistant to chemotherapy ?

Expert:  Dr. Phil, MD replied 2 years ago.
No, not really. Most respond quite well.
Dr. Phil, MD and 5 other Medical Specialists are ready to help you
Expert:  Dr. Phil, MD replied 2 years ago.
I appreciate the excellent rating.

I would be happy to help you in the future. Just ask for feedback. Thank you. :) Dr. Phil in your question opening or bookmark this page http://www.justanswer.co.uk/medical/expert-irondoc/

I greatly appreciate a positive rating in the customer satisfaction survey that you will receive via email. It is important for me to get your feedback. Thank you. :)