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Ask Family Physician Your Own Question
Family Physician
Family Physician, Doctor
Category: Medical
Satisfied Customers: 2418
Experience:  GP with over 27 years experience including emergency medicine
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Is a cea drop of 25 points after 2 rounds of chemotherpay reasonable

Customer Question

Is a cea drop of 25 points after 2 rounds of chemotherpay reasonable ? Metastic colon cancer
Submitted: 2 years ago.
Category: Medical
Expert:  Dr. K. replied 2 years ago.
The drop in points is of no significance
Expert:  Dr. K. replied 2 years ago.
A drop of 30 percent from baseline helps to exclude progression.
Expert:  Dr. K. replied 2 years ago.
Otherwise, the levels are not of much help in metatstatic colon cancer at all.
Customer: replied 2 years ago.

Ok was 65 judt before chemo started . After first round it jumped to 80 and after second round is 55.

Expert:  Dr. K. replied 2 years ago.
An initial increase often happens. Unfortunately a decrease to only 55 has no clinical meaning but if the chemo is not done, it has no meaning at all. Its best to wait until after chemo is over to test.