I have exercise intolerance, or to use my own description, my muscles seem to run out of energy with mild to moderate exertion. I can't hold a position against gravity for long. When my leg muscles are tired they shake uncontrollably, I can't grip things with my hands for long, the items slide through my fingers. I have pain in my muscles when they are tired, but this does pass at rest. I would say that there is a certain amount of weakness when I try to do certain things like climbing and descending ladders or steep steps. My nerve conduction tests were all clear, there were some abnormalities on the edge but I have not been told what they were and the muscle biopsy was only checked for polymyositis and inclusion body myositis both were negative. I'm seeing an urologist next week to see if my urine retention could be related to a muscle problem.
The person who did my email said there were some abnormalities but I never got to find out what they were. As for the strength tests yes my strength is almost normal.
Yes that is correct, though walking on flat surfaces doesn't tire me as quickly. My job tires me and when I stop working I can fall asleep quite readily in front of the television, is that the sort of tiredness you are referring to?
Sorry I couldn't continue earlier, it was gone midnight and i'd got to be up at 6.30 am to go to work. I have had time to look into the symptoms of me/cfs and it does seem feasible but I have not had a virus that would have coincided with the start of these symptoms and my symptoms have been progressing for at least 20 years, starting with shaking legs when in certain positions like bending over to tie shoe laces a position that keeps me in one position for longer than a few seconds, then I have trouble standing up again. Static, isometric exercise is my biggest problem. Does this sound right for ME.
last thing, then I will rate, my original question, regardless as to whether I have a mitochondrial myopathy or not, does the disease show in routine blood tests such as red or white blood cells or liver function, etc.?
So what does cause ME?
How long does it take for the muscle to grow back after a muscle biopsy?
After nearly 3 months I still have quite a substantial dent where I had my muscle biopsy and some pain, is this normal.
Sorry. I gave you an 'excellant' rating on 19th September, so I don't understand why you have not been paid, the fee I was charged has come off my account. I am completely satisfied with your answers so far, though I am not convinced as yet that the problem is ME and shall continue to investigated possible conditions up until my next neurology hospital appointment in December. I have been on holiday since my question on 23rd September, this is my first opportunity to write again on my computer. Tell me what I have to do to send my rating.
i have taken a photo of my biopsy dent, how do i send it to you?
For Dr Thomas MD only
No. I won't be seeing him again now, he has referred me on to one of his collegues at the same hospital. I just didn't know what to expect and if the missing muscle sample would be replaced by the body;whether it would grow back, or whether the dent would remain.
When I have to stand for any length of time, especially after any exertion,(even the day after exertion) my legs shake and I feel like they won't hold me up against gravity, so I find myself leaning or standing in strange positions and holding on to nearby objects, or just moving around all the time or finding somewhere to sit. When it first started a few years back it was diagnosed as an orthostatic type tremor and was mostly in my right leg, but now it has progressed to this feeling of weakness and unsteadiness from the waist down. Can this be a symptom of ME?
Sorry, I am trying to get things clear in my mind, I may ask the same question again in a different way. So here goes. I only need to contract my muscles for more than perhaps 10 minuets to get pain and discomfort that may not even bother me for 24 hrs or more - especially hip and thigh. For instance trying to keep myself upright, stopping body movement in a moving car, resting something on my lap to work on, sitting in some hard seated chairs, then I may have trouble using the muscles at all, not just shaking but actual inability to use the muscle - little strength. An example - while on holiday at the beginning of this month (short walks) my leg muscles were so tired by the 5th day that I could not step up on to the bus as I had the previous days - it was a little bit higher than the average stair. I did manage eventually but with much effor to the point of hurting my arms.The 6th day was quite an easy day and my muscles recovered somewhat but not completely. M.E. or not?
It is a big part of my life at the moment because it affects so many things that I try to do - particularly at work (a job that is very important to me and I don't want to let anyone down) and in hobbies. I have been trying to get a diagnosis for this problem for at least 18 months and I expect that my 'anxiety' is making it worse. But I can not allow myself to treat myself fairly with respect to rest, exercise , exceptance, without a diagnosis, until then I will consider myself as a fraud. I can't change things without knowing what is wrong, I could hurt myself more. I have no appointment with neurologist for another 6 or 7 weeks. I can make an appointment to see my GP. I have some very supportive friends especially at work, but my family, that I live with, are too old to understand anything except a proper diagnosis, I don't think they even know how I feel .If it is in my head (ie psychosomatic) then i will only get critiscism from them. Is there anywhere that I can find good information about this condition, I have purchased 2 books but they both talk about viruses, headaches, flu- like symptoms and not much about how the muscles are affected. My muscle fatigue is much more prominent than my general tiredness. I know you are not diagnosing and there is no way I would report any of this to any medic that I might consult away from the internet, but I thank you for all your information. And to be honest I have very few general symptoms of recognised anxiety, but I think I might be depressed.
Sorry if this is not your department, and perhaps this is an odd question, but how can I tell if I have muscle atrophy or if it's cellulite in my inner thigh area. It's only one patch on both legs but more severe on the right.
Would I be right in thinking that if a person was to have muscle atrophy around joints then they could have joint problems, such as buckling or displacement or just plain pain?
Are there any other reasons why a joint should buckle or 'stick' so that you can't move it?
that's a relief!
what's a request lock
I have a problem with my calf muscles, this started in my right leg but is now troubling both legs. My calf muscles are tight and hurt when I'm walking. I try to stretch them prior to exercise if I have been sitting for any length of time but I think they have permanently shrunk (it has been getting worse for several years) and stretching makes no difference. The pain isn't always there but the tightness is. If I stretch regularly the right calf particularly, it makes my ankle unstable and then it will sometimes give way when I'm walking (not made me fall yet - it just buckles). What do you think is causing this and what can I do, because it is affecting my walking and working.