There are many differences with respect to the cause, the mechanism of development of disease, the clinical features, and the treatment. What are you looking for?
All the three CIDP, SLE, and GBS are immunologic mediated diseases. In most cases abnormal antibodies are produced that cross-react with normal tissues in the body. In GBS the target is peripheral nerves. CIDP can be considered as the chronic equivalent of Guillain-Barré syndrome. SLE most involves the skin, joints, kidneys, blood cells, and nervous system
Due to these abnormal immunologic actions there is development of disease and clinical features.
In GBS there is muscle weakness with weakness involving the lower limbs initially before progression of weakness to the upper limbs. Also there is numbness and abnormal sensations. CIDP is similar to GBS clinical features but this is chronic with periods of worsening and improvement usually last weeks or months.
In SLE clinical features due to involvement of most of the organ systems can be present along with fever.
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Testing is done to know the abnormal antibodies by doing assays for antibodies. However diagnosis is suspected based on the clinical features and the physical examination. Electromyography (EMG) and nerve conduction studies (NCS) may be done. Lumbar puncture with examination of CSF may also be considered. Sometimes biopsy of muscle or nerve may be done.
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Yes they are.
In all of these conditions symptoms occur that make most patients to consult a doctor after few days to weeks.
They may have these conditions life long. There is no cure and these are chronic conditions. And sometimes even in GBS there are complications and sequela which last life long.
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This requires a good past history of the symptoms and then physical examination needs to be done to know which muscles, which nerves, and which organs are involved. Then based on laboratory investigations diagnosis is done. Sometimes response to treatment also helps in diagnosis.
Yes they are the same.
There is not a single test but multiple tests that need to be done which I have mentioned in my earlier answer.