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Dr Anil Kumar
Dr Anil Kumar, Doctor
Category: Medical
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Experience:  M.D with over 30 years of experience in practice.
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I am taking Perindopril 8 mg and Indapamide 2.5 for high

Resolved Question:

I am taking Perindopril 8 mg and Indapamide 2.5 for high blood pressure. Can I take 5 - 7 mg valium as a one off, to fly/ Can I take a mix of aspirin and paracetamol for pain for occasional headaches? thanks wendy finney
Submitted: 11 months ago.
Category: Medical
Expert:  Dr Anil Kumar replied 11 months ago.

Hello and thanks for trusting me to help you. I am a board certified consultant with over 30 years of experience.

There is no interaction in case you take diazepam(valium) with your blood pressure pills so you can take it only once while air travel.

However you should avoid aspirin with Perindopril 8 mg and Indapamide 2.5 mg.

Only take Tylenol/paracetamol with them safely for occasional headache.

Let me know if you have any further query so we can discuss it thoroughly in every aspect.
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Customer: replied 11 months ago.
Can you tell me what reaction there may be with aspirin, as this aspirin/paracetamol pain killer mixture is most effective for headaches more than paracetamol alone which doesn't seem to work for me. thanks. wendy finney
Expert:  Dr Anil Kumar replied 11 months ago.

Thanks for the follow-up.It’s my pleasure.

Aspirin decreases effects of perindopril by opposing drug effects.

Potential for reduced effectiveness in lowering blood pressure.

If you want to take it then take them with a gap of 6 hours.

Hope this helps.
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Customer: replied 11 months ago.
Thank you that is very helpful. I rarely take more than one dose of 500mg aspirin/paracetamol for a headache. My average blood pressure is 152/82 and I have just started taking the Indapamide in combo with perindopril so am waiting for the new drug to kick in and see if it lowers my blood pressure effectively. I am 68 and reasonably fit with no health problems apart from the blood pressure. thanks
Expert:  Dr Anil Kumar replied 11 months ago.

You are most welcome.

Kind regards,

Dr.Anil