This is Dr. David
there can be drug interaction risks with sertraline and amitriptyline taken together.
the combintation can increase levels of amitriptyline levels
and can increase risks for SIADH syndrome of inappropriate anti diuretic hormone and can cause low blood sodium levels.
there are also small risks for serotonin syndrome.
you should talk to your doctor about these issues.
let me know if you have other questions.
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