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Yes your son has been advised hepatitis B vaccination to keep him safe from Hepatitis B infection. The chances of having any major side effect with Hepatitis B vaccine are very less. Hepatitis B is a blood borne infection and can be transmitted through IV drugs,blood transfusion,sexual contact with Hepatitis B patient and some dental procedures or even surgeries if equipment is not sterilized properly .Vertical transmission also occur from mother to newborn. Your son has a CKD as well and can require dialysis at some stage so to minimize chances of Hepatitis B infection he should be vaccinated.
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