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Dr. Bob
Dr. Bob, Neurologist (MD)
Category: Neurology
Satisfied Customers: 5118
Experience:  Neurology & Int Medicine (US Trained): 20 yrs experience
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I have had all tests required in NZ for suspected:

Customer Question

I have had all tests required in NZ for suspected: stroke..slightly slurred speech (negative); CAT scan (neg); MRI (negative); SEVERAL BLOOD TESTS, ( one sent to Oxford, UK for diagnosis (negative) NERVE CONDUCTION TESTS (negative)...but negative to what?...neurologists don't know. This is extremely frustrating...going on for about 12 months. Self diagnosis (I live with my symptoms 24/7) suggest MG...I only have trouble articulating clearly,chewing,drooling from excess saliva after taking Mestinon and swallowing...no eye droop etc., but neurologists will not hear of it. I suspect they are cranky with me for daring to do my own research! I have asked for prednisone treatment, recommended by international websites, but a big NO! I was diagnosed with osteoporosis after a bone density scan when living in Australia, (following a fall after tripping over my two dogs after a long-haul flight home from UK in 1980) and osteo arthritis for approx. 20 years, am careful with movement and still no broken bones! All saying I will end up in a wheelchair, but I am now left with no quality of life, cannot go out in public for coffee or meals because of dreadful drooling after being prescribed Mestinon which did not work, and my speech is now so bad, I cannot contain any understandable conversation...have always had very clear, concise diction. Have been a teacher for 34 years, a singer and speaker to groups...can now do nothing! told to simply enjoy life!! My question is...if prednisone is administerd correctly and according to all documented reports, carefully and regularly monitored, what are the chances of me regaining ANY quality of life again? I now live in NZ, am 82 years old and was looking forward to another 15-20 years active life!! I live independently, drive my car everywhere and have always kept good health. I am a positive thinker, but this has really got me down. My family is supportive, but specialists have scared the hell out of them with this information that I will end up in a wheelchair if I am prescribed prednisone!! I will really appreciate your thoughts and look forward to your reply with grateful thanks. Margaret xxxx

Submitted: 2 years ago.
Category: Neurology
Expert:  Dr. Bob replied 2 years ago.

Dr. Bob :

Hi Margaret. Have you been checked for anti–acetylcholine receptor (AChR) antibodies? This is a reliable test for diagnosing autoimmune myasthenia gravis (MG).

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