How JustAnswer Works:

  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.

Ask Dr. Bob Your Own Question

Dr. Bob
Dr. Bob, Neurologist (MD)
Category: Neurology
Satisfied Customers: 5219
Experience:  Neurology & Int Medicine (US Trained): 20 yrs experience
61817858
Type Your Neurology Question Here...
Dr. Bob is online now

My son takes keppra 1000mg twice daily. He has been

Resolved Question:

Hi, my son takes keppra 1000mg twice daily. He has been prescribed cetrine 10mg daily. Is this safe to take with the keppra?
Submitted: 10 months ago.
Category: Neurology
Expert:  Dr. Bob replied 10 months ago.

Hi John. Cetrine is a brand name version of the common antihistamine cetirizine.

This medication is safe to take with Keppra at usual doses. No adverse side effects would be expected.

Customer: replied 10 months ago.
Please read information leaflet attached to cetrine. If a patient is predisposed to seizures, then cetrine 10mg daily may be dangerous for that patient.
Expert:  Dr. Bob replied 10 months ago.

Hi John. There are a lot of medications that contain this warning. Manufacturers often include it to cover themselves in the very unlikely event of a seizure. While it is always a possibility, I have never seen this medication trigger a seizure. Keep in mind that alcohol can also be dangerous in those predisposed to seizures. And drinking too much water can also trigger a seizure.

Customer: replied 10 months ago.
Thank you Dr. Bob. I really appreciate you taking the time to reply. My own research indicates the following:
"Seizures or convulsions have been reported in the literature with some first-generation antihistamines (chlorpheniramine, diphenhydramine, pheniramine and pyribenzamine) as well as with some newer-generation antihistamines (astemizole, cetirizine, fexofenadine, loratadine and terfenadine) (1-3). According to the US Food and Drug Administration Adverse Event Reporting System (July 1999), convulsions associated with cetirizine, fexofenadine and loratadine accounted for 2.5%, 3.1% and 2.1% respectively of the total adverse events reported with these drugs". (Reference: http://apps.who.int/medicinedocs/en/d/Js4952e/3.7.html). Our son suffered encephalitis in 2010 and was seizure free on Keppra up to October 2015. He was prescribed cetrine 10mg daily and has suffered 2 major seizures in the last 6 monrths. Both my wife and I are desperately searching for reasons and realise how difficult it is to pinpoint any specific trigger. Again many thanks. Your sincerely, John
Expert:  Dr. Bob replied 10 months ago.

Did his seizures occur within 36 hours of taking the cetrine (while it was in his bloodstream)? Has there been any seizure activity off the cetrine?

Dr. Bob, Neurologist (MD)
Category: Neurology
Satisfied Customers: 5219
Experience: Neurology & Int Medicine (US Trained): 20 yrs experience
Dr. Bob and other Neurology Specialists are ready to help you

What Customers are Saying:

 
 
 
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me FROM a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O.
< Previous | Next >
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me FROM a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O.
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C.
  • This expert is wonderful. They truly know what they are talking about, and they actually care about you. They really helped put my nerves at ease. Thank you so much!!!! Alex
  • Thank you for all your help. It is nice to know that this service is here for people like myself, who need answers fast and are not sure who to consult. GP
  • I couldn't be more satisfied! This is the site I will always come to when I need a second opinion. Justin
  • Just let me say that this encounter has been entirely professional and most helpful. I liked that I could ask additional questions and get answered in a very short turn around. Esther
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C.
 
 
 

Meet The Experts:

 
 
 
  • Dr. F

    Dr. F

    Board Certified MD

    Satisfied Customers:

    266
    Neurosurgeon with more than 20 years experience in practice and teaching.
< Previous | Next >
  • http://ww2.justanswer.com/uploads/BrainLifeDoc/2010-10-04_004701_AMF_2008_2_pix.jpg Dr. F's Avatar

    Dr. F

    Board Certified MD

    Satisfied Customers:

    266
    Neurosurgeon with more than 20 years experience in practice and teaching.
  • http://ww2.justanswer.com/uploads/TO/TOHfan1/2012-3-3_11610_strokedoc.64x64.jpg Stroke Doc's Avatar

    Stroke Doc

    Board Certified Physician

    Satisfied Customers:

    41
    I am board-certified in Neurology and the subspecialty Vascular Neurology.
  • http://ww2.justanswer.com/uploads/PR/pradocs/2012-7-23_23649_201272323220JApicture105x113.64x64.jpg Dr. Bob's Avatar

    Dr. Bob

    Neurologist (MD)

    Satisfied Customers:

    1500
    Neurology & Int Medicine (US Trained): 20 yrs experience
  • http://ww2.justanswer.com/uploads/HE/healthydoc/2011-7-22_193154_LevGrinman2.64x64.jpg healthydoc's Avatar

    healthydoc

    Board Certified Physician

    Satisfied Customers:

    325
    Board Certified U.S. Neurologist
  • /img/opt/shirt.png RH's Avatar

    RH

    Board Certified Neurologist

    Satisfied Customers:

    1944
    Expert in various areas of Neurology
  • /img/opt/shirt.png Brainmaster's Avatar

    Brainmaster

    Board Certified MD

    Satisfied Customers:

    58
    ABPN certified. 6 years of outpatient general neurology practice experience. No malpractice cases
  • /img/opt/shirt.png braindr11's Avatar

    braindr11

    Board Certified Physician

    Satisfied Customers:

    43
    Neurologist with outstanding expertise