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Hi John. If the cetrine was going to provoke a seizure it would have done so before 7 months! There are so many other more likely factors that could be responsible for his breakthrough seizures. Do you know what his keppra levels were at the time of the seizures? Many things can temporarily lower blood levels and trigger a seizure. If he is now seizure free off the cetrine, then obviously you would not want to start him back on it. On the other hand, if he does have another breakthrough seizure this would be evidence of something else going on...something that would rquire a new neurological work up.