Your previous irregular periods and now no period in the past 6 weeks suggest that you probably don't ovulate regularly. Fortunately, this is the easiest fertility problem to help.
There are pills called Clomid that you can take each month to help you to ovulate.
I would recommend that you see your doctor for help to both confirm that you're not ovulating and for a prescription for pills to help you to do so.
Neither methotrexate nor etanercept affect fertility as far as we know. Methotrexate can cause birth defects if you got pregnant while taking it, but not afterwards.
Etanercept is a category B medication, meaning that it's safe during pregnancy as far as we know. Best wishes.
Is it possible that the copper coil was the cause of the irregular periods? Rather than not ovulating regularly? Is it at all possible that its just taking time to get a cycle and after removing the mirena?
The copper coil can cause periods to be heavy, but won't affect how regular the periods come. That's caused by your ovaries and whether or not you're ovulating.
Usually fertility returns soon after the mirena is removed. If you had regular periods before using the mirena, it might be worthwhile waiting longer to see if the regular periods resumed. In your case, I think you weren't ovulating much before, and you're still not ovulating much. The reason has nothing to do with the mirena. Often we don't know the reason. Some women don't ovulate regularly.
I appreciate it has been a while but i'm still having issues, regularity hasn't happened yet. I've had hormone profile checked and that's normal, I've also had a TV scan that is normal. i'm really struggling to get an appointment with my GP do you know if it's possible for me to self refer to get clomid treatment privately? or what would my next step should be?
You don't really need a lot of hormonal tests or scans. You just need clomid. You need to see a doctor for it, public or private.