What are your outbreaks like? Do they always occur in the same place? How long do they last? Have they been confirmed by a herpes culture? Thank you.
Acyclovir resistance is rare.
I am suspicious that all your outbreaks are not due to herpes. Genital herpes doesn't really recur more than once a month.
I would recommend that you see your doctor while an outbreak is present to have a herpes culture done. Then your doctor can figure out what is really going on.
Yes. Acyclovir is not perfect. Women can have outbreaks, but usually many fewer outbreaks than otherwise.
I suspect that it has nothing to do with acyclovir. Your outbreaks are not from herpes.