Hi there. Thank you for your question. I will be helping you out with your queries
I am really sorry to learn about your wife.
Unfortunately anaplastic cancer is the most aggressive of all the thyroid cancers.
so, no treatment available? something like monoclonal antibody treatment?
Anaplastic thyroid cancer is highly unlikely to be curable either by surgery or by any other treatment modality
Radiation therapy usually combined with chemotherapy. No role of monoclonals.
There is a role for monoclonal antibodies but that is in investigational phase and not proven effective as yet.
These include new drugs, such as fosbretabulin (a type of combretastatin), bortezomib and TNF-Related Apoptosis Induced Ligand (TRAIL),
Do radiation combined with chemotherapy would be a solution or just a palliative treatment?
Usually only a palliative treatment.
In your wife's case its most likely to be palliative since it has spread to the trachea and the oesophagus.
are you with me?
Right, so ... those new drugs you mentioned, they're also ineffective?
They are in trial phase
So we do not know for sure.
How does one participate in the trials?
You would have to ask the hospital in your area if there is any trial going on there.
Here is a website which you can refer to for possibly placing her on a drug trial
Here is another web link.
Are you with me?
this link gives you a detail on the trials that have been done and the results
This session is open to your questions until you are satisfied.