This is Dr. David
I am sorry for your grandparent who was found to have multiple myeloma
multiple myeloma is a cancer if the plasma cells which come from the bone marrow
these cells make immunoglobulins which are protein parts which make up antibodies for the body's immune system.
it sounds like you are reading from a bone marrow biopsy report.
assessment of patients with multiple myeloma take into account several factors including the results of bone marrow biopsy, the results of skeletal survey and xrays of bones to see if the cancer has spread to bones, blood plasma electrophoresis testing to check protein levels in the blood and to check how high the M protein spike may be (the higher the spike, the more plasma cells are making this myeloma protein) and overall performance status of the patient and kidney function
patients who have multiple myeloma can live for years and years with treatments to suppress their myeloma
if the cancer has spread to the bones, 1-2 weeks of radiation therapy to those areas often can help kill the plasma cell cancer there and help decrease pain.
you should go with your grand parent to the doctor's appointment to support them and to learn about the testing results from the doctor and ask about the other tests I mentioned.
let me know if you have questions.
I'm not sure what you mean by "one lot of cancer cells"
diagnosis of multiple myeloma is not a death sentence.
it can be treated.
is she starting to get treatment for her MM?
no, we can't tell the stage of her MM from the biopsy report from her bone marrow
we need more information including the results of her skeletal survey.
multiple myeloma cancer isn't staged in the same way as other cancers.
we assess the level of the cancer by looking at the M protein levels in the blood on protein electrophoresis
and if the bone lesions are progressing or not on xray scans.
let me know if you have other questions.
if done for now, please leave positive rating of 3-5 stars so I can get credit for helping you today
we only get credit for helping clients after positive feedback
you can always reach me directly with "a question for Dr. David" in the medicine or oncology categories if you have other questions
here is my website if you need to reach me:
Thanks for using JustAnswers.com
Revised ISS (R-ISS) is the revised international staging symptom for multiple myeloma.
Stage I includes ISS stage I (serum 2 - microglobulin level 3.5 mg/L and serum albumin level 3.5 g/dL), no high-risk CA [del(17p) and/or t(4;14) and/or t(14;16)], and normal LDH level (less than the upper limit of normal range)
R-ISS III includes ISS stage III (serum 2 -microglobulin level 5.5 mg/L) and high-risk CA or high LDH level;
and R-ISS II includes all the other possible combinations
MRC is Medical Research Counsel.
R-ISS is the Revised International Staging System (R-ISS) for multiple myeloma that incorporates the original staging system with chromosomal abnormalities (CA) R-ISS stage I is serum beta2-microglobulin level < 3.5 mg/L and serum albumin level of 3.5 g/dL or greater, no high-risk CA [del(17p) and/or t(4;14) and/or t(14;16)], and normal LDH level (less than the upper limit of normal range)
R-ISS III: includes ISS stage III (serum beta2-microglobulin level > 5.5 mg/L) and high-risk CA or high LDH level
R-ISS II: includes all other possible combinations.
it sounds like her R-ISS stage is I but it says 2.
no, that is not bad.
her multiple myeloma can still be treated and controlled for years and years.
again, multiple myeloma can be treated and controlled for years, but it is not curable without a bone marrow transplantation
myeloma can progress and spread and become resistant to treatment after a period of time.
for every patient, this period of time can be different.
no. favorable risk means her multiple myeloma should be controlled with treatment for a longer period of time.
how old is your grand parent?
it can be difficult to impossible to try to accurately predict how long she will live for
even her own doctors will not be willing to do that
because no way can play god that way