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Hello, my name isXXXXX I can try to help answer your questions about your dog.
So sorry to hear this happened. Unfortunately bone cancer (ostosarcoma - most commonly) is a cause for these pathological fractures.
Amputation is the best scenario for these patients. If your dog is a very active, physically fit (trim) animal, he will likely do very well with one front leg amputated.
I heard one of my collegues say once (an I liked the quote) so I will use it here that dogs and cats are born with 3 legs and a spare.
Meaning they do very very well on three legs.
The main concern is that osteosarcoma is a metastatic disease which can have already spread prior to amputation.
I would recommend a chest x-ray, and abdominal ultrasound to rule out metastasis of cancer before you put him through the amputation. If metastases are already present, it's probably not a good idea to put him through a major procedure such as amputation.
If there are no mets present, go ahead with the amputation and possibly follow up chemotherapy protocals.
Hopefully this helps.... please feel free to respond.