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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog
Satisfied Customers: 62241
Experience:  University of California at Davis graduate veterinarian with 48 years of experience.
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My dog ate ibuprofen 2 days ago and keeps being sick since

Customer Question

My dog ate ibuprofen 2 days ago and keeps being sick since
Submitted: 1 month ago.
Category: Dog
Expert:  Dr. Michael Salkin replied 1 month ago.

Dr. Michael Salkin is typing. Please be patient.

Expert:  Dr. Michael Salkin replied 1 month ago.

I'm sorry to hear about this with your dog. How much does your dog weigh and how many mg of ibuprofen were ingested, please?

Customer: replied 1 month ago.

14kg and about 10 tablets

Expert:  Dr. Michael Salkin replied 1 month ago.

2,000 mg/14 kg = 143 mg/kg. Ibuprofen overdose can cause gastrointestinal, renal, and central nervous system effects. Doses of 25 mg/kg or more often lead to gastrointestinal problems and ulceration, manifested as vomiting, diarrhea, or abdominal pain. Doses approaching 175 mg/kg increase a dog's risk of developing acute renal failure, but older dogs or those with preexisting renal compromise may exhibit renal failure at lower doses.

Regrettably, your dog's vomiting can indicate not only gastrointestinal ulceration but also kidney failure. Your dog needs the attention of a vet at your earliest convenience. Kidney function tests will be performed and an oral intestinal coating agent such as carafate will be given after an injectable antiemetic and antacid are given. IV fluids may be needed if kidneys are badly affected.

Please respond with additional questions and concerns if you wish.

Customer: replied 1 month ago.

The vomit looks like bile. He's still eating, drinking and playing as normal. I will call vet in the morning is there any sign I should be looking out for the now?

Expert:  Dr. Michael Salkin replied 1 month ago.

His behavior should rule out kidney involvement.  The presence of the blood in the vomitus would be worrisome from bleeding ulcer.

Please continue in this conversation if you wish.