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Hi there,I am an experienced Medical Specialist.I am here to address your concerns and provide great service.You have very complicated symptoms and have been going on for a while.
Given the fact, Pentasa allergy has been reported and can trigger wide spread immune reaction.
The medication should be discontinued first.
An allergy specialist or immunologist can be consulted with to test for pentasa sensitivity specifically as next option.
You may see gradual improvement once you are off the medication.