Have you considered appointing a professional trustee (solicitor) to run the trust alongside your brother? With two trustees and one being a professional, the capacity of the potential future carer of your son to manipulate the funds is minimalised.
This ensures that your son remains the beneficiary, and the professional trustee could take over the running of the fund should something happen to your brother in the future. The trouble with having your brother as the beneficiary in my view is that it is also possibly open to manipulation from other people connected to your brother financially, for example a spouse.
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