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what cause renal bleeding during acne treatment with ORATA

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Hi and welcome to Just Answer.

I believe that you mean rectal bleeding. This medication is associated with rectal bleeding either during or after treatment due to inflammatory bowel disease. This is an inflammation of the colon.

Symptoms may be abdominal pain, rectal bleeding, or severe diarrhea. The symptoms may begin during treatment or even after treatment is discontinued. If this occurs, you should report it to your Dr immediately and seek treatment.

While this side effect is rare, it can occur. I hope this information is helpful to you.
Thank you for your rating.