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Dr. Phil, MD
Dr. Phil, MD, Board Certified Physician
Category: Medical
Satisfied Customers: 58700
Experience:  GP in the United States
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If chemotherapy is working does a person have more side effects

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If chemotherapy is working does a person have more side effects ?
Hello. I'm Dr. Phil, licensed and practicing internist. Excellent service is my goal.
Thanks for this question. Can you explain what happened?
Customer: replied 2 years ago.

Well my father has so far had 2 rounds if chemo for metastic colon cancer . He was a stage 3 and now 4 as has liver mets and few small peritoneal nodules .

he had oxyplatin and raltitrexed . He's just not able to eat , his appetite has gone , as a result lost 5 kg in 5.5 weeks , fatigue and had chills and slight fever for 2 days but that's ok now .

also his ALP level has gone from 75 to 175 after first chemo round .

That doesn't mean it is working or not working. That is just a side effect of chemo.
Customer: replied 2 years ago.

But can a person complete lose appetite ?

absolutely. This is common with chemo
Customer: replied 2 years ago.

I thought it may be cancer progression causing him to not eat

Not necessarily. It could be the chemo too
Customer: replied 2 years ago.

Cea has jumped from 65 to 80 after first session . ALP level raised too after 1 round to 175 does this meN it's not working ?

I think it is a sign the cancer is progressing unfortunately. I'm sorry
Customer: replied 2 years ago.

That's what I think otherwise it would decrease right ?

that is correct. AGain, I'm very sorry
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