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Dr Basu
Dr Basu, Experienced Specialist
Category: Medical
Satisfied Customers: 29282
Experience:  MD
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Lately my skin feels weird expecially in hot whether. My

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Hi. Lately my skin feels weird expecially in hot whether. My skin feels tick and produces stinking smell like rotten body. My Gp cant come up with anything. Please what steps do u suggest i take asap. Thanks
Hi there,
This is Dr Basu, Experienced Specialist.
I am here to address your concerns and provide great service.
The most common causes are diabetes, and hypothyroidism.
They should be checked with fasting blood sugar, TSH levels.
The next likely possibility is a metabolic disorder called trimethylaminuria.
This is due to the genetic defect called FMO3 enzyme deficiency.
FMO3 is required to convert trimethylamine to trimethylamine oxide.
Measurement of urine for the ratio of trimethylamine to trimethylamine oxide is the standard screening test. A blood test is available to provide genetic analysis. The prominent enzyme responsible for TMA N-oxygenation is coded by the FMO3 gene.
Ways of reducing the fishy odor may include:
Avoiding foods such as egg yolks, legumes, red meats, fish, beans and other foods that contain choline, carnitine, nitrogen, sulfur and lecithin
Taking low doses of antibiotics such as neomycin and metronidazole in order to reduce the amount of bacteria in the gut
Using slightly acidic detergent with a pH between 5.5 and 6.5
Best wishes,
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