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This is Dr. David. I am reviewing your question now and will be with you momentarily.
I am sorry you have metastatic resistant prostate cancer.
rising PSA very quickly can be a sign your prostate cancer is growing and that the clinical trial agent is not working.
do you have metastatic disease in your organs or just in your bones?
do you have pain in your bones?
have you tried xtandi or zytiga second line anti-androgens?
have you received taxotere chemotherapy?
have you tried Xofigo radioactive radium 223. these are clinically proven treatments for patients who have castrate resistant prostate cancer which could help.
you take pain killers, but you say you don't have bone pain?
I have to see a patient right now. but I can call you in 15-20 minutes.
best of luck to youYou can always reach me with "a question for Dr. David" in the medicine or oncology categories if you have other questions.Here is my website: http://www.justanswer.com/medical/expert-dr-david/Thanks for using JustAnswers.com