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Have you consulted with a Doctor for this? If so, what is this doctors specialty?
Has this happened before in your life?
Is anything going on that may be exacerbating/causing the depression?
If the Duloxetine has not worked by now you will probably need a second type of antidepressant or a different one.I'm not sure if adding 5HT will do much to improve things at this point.
I would talk to your MD to see if she would be willing to switch your medications around.
You might also want to look into getting some talk therapy help from a PhD level person.
Does this make sense to you?
I am happy to be able to help you today. If you would be so kind, please help me get credit for my efforts in answering your questions and press the excellent feedback button for this encounter. And, don’t forget, I work for tips. I would also be happy to continue to answer any more questions you have until we have resolved your concern.
Dr. Rick MD FACS
Zoloft (sertraline) is very good and is used by millions worldwide with excellent results.
It's safe for you to press the positive feedback button now if you so desire. And, never fear, even after you press that button I'll still be right here to continue helping you, but, as I do work for tips, I want to make sure you are happy before rating me.