Thank you for getting back with the requested necessary information.
From your symptom analysis and correlation with with the history that I have gathered from you I feel that you may be having auto immunity....undefined autoimmunity.
ANA can be negative is sero-negative variety of auto immune phenomenon.
When it is working normally, the body's immune system kills germs or viruses and fungi. Sometimes, something goes wrong and the immune system starts to attack own body cells. That is called an autoimmune response. It is what happens in auto immunity. In other words, if you have atuo immunity, your body is attacking itself.
Symptoms can be -
Feeling tired or weak
Lose or gain weight
Rash on their nose and cheeks shaped like a butterfly, especially if they spend time in the sun
Joint pain and stiffness
Swelling in the hands, feet, belly, or around the eyes
Urine that looks brown (tea-colored) or foamy
Sores in the mouth
Cold fingers or toes that turn pale or blue
Your doctor might perform some special tests like antinuclear antibody and anti double stranded DNA, apart from the routine blood test workup.
Treatment includes non-steroidal anti-inflammatory drugs, steroids, immuno-modulatory drugs and biological agents.
May I suggest you discuss this possibility with your primary care physician and get yourself appropriately evaluated and managed please.
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