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Hi there,I am an experienced Medical Specialist.I am here to address your concerns and provide great service.Omeprazole is used to treat Barrett's esophagus.
Hence, it use may cause missed diagnosis due to changes in epithelium.
Regarding cancer lesion, omeprazole will not affect the findings.
Omeprazole will also mask the H pylori infection --can be false negative test.
Usually 2 week wash out by stopping PPI is recommended before endoscopy.