Rest Leg Syndrome can develop as a result of certain conditions, particularly iron deficiency and peripheral neuropathy. Other causes of RLS are folate or magnesium deficiency, amyloidosis, diabetes mellitus, lumbosacral radiculopathy, or vitamin B-12 deficiency. Following investigations are advised;
1) A complete iron panel including iron levels, ferritin, transferrin saturation, and total iron-binding capacity.
5) thyroid-stimulating hormone (TSH),
6) vitamin B-12, and folate.
These investigation results will help to treat the primary problem so symptoms are resolved.
Following measures usually are helpful;
1) Avoidance of caffeine, alcohol, or nicotine (if one takes them).
2) Exercise before the bedtime
a) Pramipexole (Mirapex)
b) Ropinirole hydrochloride (Requip).
Following treatment approaches are recommended if your present medications are not helping (called refractory RLS):
1) Change to gabapentin
2) Adding a second medicine like gabapentin, benzodiazepines, or an opioid
3) Change to a high potency opioid or tramadol
In addition to the above non-pharmacologic therapy comprises the following components:
1) Iron replacement therapy
2) Mental alerting activities such as video games or crossword puzzles, may reduce symptoms at times of boredom.
I wish your symptoms resolve soon.
I would be happy to assist you further if you need any more information.
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