Black ink not printing. have changed ink holder and run the

Thank you for confirming.
These symptoms point to either a clogged/contaminated print head, or a faulty print head.
The initial cleaning program you tried was appropriate. I would suggest running it at least once more though. If it still doesn't print anything, you’ll need to do a manual cleaning.
I have to caution you up front though that the manual cleaning process is messy and time consuming. It also has a low chance of success, if you see no improvement at all from the automated cleaning. It is most likely a hardware failure (bad head) which the cleaning can’t fix, as printheads are a wear item and do fail with time/use.
Realistically, it's probably time for a new printer. The next step would be replacing the head, and while it is an inexpensive part, it isn't a guaranteed fix. It may just as easily turn out to be a bad logic board that would run $200+ to fix, and even if you did other components like the absorber system, rollers, etc are at the end of their life. Because you can buy a brand new printer with updated features and a fresh warranty for about $80, that would be the more practical investment for most people.
That said, it doesn’t hurt to try, if you wish. Let me know how the built in cleaning function works, and I’ll guide you through the manual steps next, or I can help with ordering parts or recommend replacement options if you prefer.
Nathan