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Good morning, I am Laura, one of the UK vets.
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If mites have been treated and infections ruled out, it may be that Billy has chronic ulcerative skin disease. It causes itching and scabbing and unfortunately I have never been able to cure it. I used to breed mice and this was one of the reasons I stopped, I hated seeing them so itchy.
There are things you can try - switching to paper or hemp bedding over shavings, spraying the inside of the cage base with household flea spray and allow to dry (tends to reduce mite populations in bedding and food) and possibly steroid medication (tiny bit of dog tablet on a tiny bit of peanut butter every day).
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The easiest this to find is Xeno 50 spot on. What mice do you have? Are the pet shop line or show type mice? The pet shop mice are about 30g, the show type mice can be 80-90g.
Xeno is dosed according to weight.
I also use a household flea spray and spray the inside of the cages. You need to let it dry before putting the mice back in. It greatly reduces the mites coming in on bedding or in food.
They will be about 30g then.